About the LP8.1: Based COVID-19 Vaccines (Spikevax and Comirnaty) for 2025-2026

About the LP8.1-Based COVID-19 Vaccines (Spikevax and Comirnaty) for 2025-2026

The LP8.1 is the official antigen code for the currently authorized and available monovalent COVID-19 mRNA vaccine formula targeting the KP.2 variant. Updated versions of both Moderna's Spikevax and Pfizer-BioNTech's Comirnaty using this LP8.1 (KP.2) formula have been approved for use in many regions worldwide for the 2024-2025 vaccination campaign, following the scientific and regulatory consensus on the need for a closer match to circulating viruses.

Why Was the Vaccine Updated to the LP8.1 (KP.2) Formula?
Why Was the Vaccine Updated to the LP8.1 (KP.2) Formula?

The update from previous formulas (like the XBB.1.5 and initial JN.1 versions) to the KP.2-specific LP8.1 formula is a direct scientific response to viral evolution:

  • Superior Match to Circulating Virus: By late 2024, variants derived from the JN.1 lineage, primarily KP.2 and KP.3, made up the vast majority of global COVID-19 cases. Vaccines designed to match the spike protein of these dominant strains are scientifically proven to stimulate a more effective immune defense.

  • Countering Immune Escape: The KP.2 variant possesses specific mutations that allow it to partially evade antibodies generated by older vaccine formulas. The LP8.1 update is engineered to "re-train" the immune system to recognise and neutralise these newer variants more effectively, restoring a higher level of protection against infection and severe disease.

  • Authoritative Recommendation: This update was formally recommended by global bodies, including the World Health Organisation (WHO), and mandated by regulators like the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA) for the 2024-2025 season to ensure optimal public health protection.

Who Should Get the Currently Available LP8.1 (KP.2) Vaccine?
Who Should Get the Currently Available LP8.1 (KP.2) Vaccine?

Health authorities globally recommend the updated 2024-2026 COVID-19 vaccine for broad population protection. While you should always follow local official guidance, general recommendations include:

  • All adults and adolescents (typically aged 12 and older).

  • Individuals at higher risk of severe illness, including:

    • Adults aged 65 and older.

    • People of any age with chronic underlying health conditions (e.g., diabetes, heart or lung disease).

    • Individuals who are immunocompromised.

    • Pregnant individuals.

  • For most people, a single dose of the updated vaccine is recommended if it has been at least 2-3 months since their last COVID-19 infection or vaccination.

Current Global Status and Availability of LP8.1 Vaccines
Current Global Status and Availability of LP8.1 Vaccines

The LP8.1-based vaccines are authorized, approved, and currently being administered in multiple regions.

  • United States & Canada: The FDA authorized and Health Canada approved the KP.2-targeted Moderna and Pfizer-BioNTech vaccines in October 2024. They have been available for the 2024-2025 season since then.

  • European Union: The European Commission granted marketing authorization for Comirnaty Omicron JN.1 (KP.2) and Spikevax's equivalent in late 2024.

  • United Kingdom, Australia, and Other Regions: National regulators have similarly approved and are offering these updated KP.2 vaccines.

  • Hong Kong: Following the global standard, the Hong Kong SAR Government has incorporated the JN.1-lineage vaccines into its vaccination program. Marina Medical provides the Comirnaty® Omicron JN.1 (KP.2) vaccine and Moderna (Spikevax) LP.8.1  to eligible individuals. For enquiries or to arrange a vaccination, please contact our clinic directly.

References
References
  1. European Medicines Agency (EMA): "EMA recommends approval of Comirnaty Omicron JN.1 (KP.2)" (Press Release, November 2024).

  2. U.S. Food and Drug Administration (FDA): "FDA Authorizes Updated COVID-19 Vaccines for 2024-2025 Season" (News Release, October 2024).

  3. Moderna, Inc.: "Moderna Announces FDA Authorization of Updated Spikevax for 2024-2025 Season" (Press Release, October 2024).

  4. Government of Hong Kong, Centre for Health Protection: "Latest Arrangements of COVID-19 Vaccination Programme" (Official Web Page, regularly updated).

2025-26 Government Vaccination Programme
2025-26 Government Vaccination Programme

Government Programme Overview

To protect public health and facilitate the gradual return to normalcy, the Government has implemented a territory-wide COVID-19 Vaccination Programme that provides free COVID-19 vaccines to eligible individuals.

Local data show that COVID-19 vaccination is highly effective at reducing the risk of severe illness and death after infection. The World Health Organisation (WHO) also recommends that high-risk individuals receive booster doses on time to reduce the risk of severe disease and death.

Latest Vaccination Arrangements (As of June 2026)

Currently, the LP.8.1 vaccine provided under the programme for children and adults will expire in mid-July and early September this year, respectively. Existing vaccination services will continue until the following dates:

Age Group Vaccination Service End Date
Individuals aged 6 months to 11 years 10 July 2026
Individuals aged 12 or above 5 September 2026

⚠️ Important Note for Young Children: For children aged 6 months to 4 years without prior infection, if they do not receive their first dose on or before 12 June 2026, they will not be able to receive the second dose by 10 July to complete the initial doses. They may still book their first dose now and receive the second dose once the vaccine supply resumes.

A new batch of vaccines will arrive in Hong Kong successively in the fourth quarter of 2026, and vaccination services under the Programme will resume in an orderly manner.

Eligible Persons

The following priority group are eligible to receive a free booster under the government covid19 vaccination programme:

Priority Group Details
RCHE residents Residents of Residential Care Homes for the Elderly
Community-dwelling elderly Aged 65 years and above
Persons with underlying comorbidities Aged 50 to 64 years
Immunocompromised persons Aged 6 months and above
Pregnant women Once during each pregnancy
Healthcare workers Encouraged to receive vaccination for personal protection

Get In Touch

For any enquiry, please call +852 3420 6622, Whatsapp +852 5228 0810, or info@marinamedical.hk

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